Each tablet contains: Indomethacin 25 mg Excipients: Cornstarch, lactose monohydrate, magnesium stearate, sodium carboxymethyl starch. Pack of 24 tablets.

Indomethacin is indicated in all natural rheumatic processes, ankylosing and osteoarthritis. In musculoskeletal diseases (bursitis, tendinitis, synovitis and tenosynovitis). In rheumatoid arthritis, Indomethacin reveals better results in acute cases, with pronounced anti-inflammatory component. Inflammatory processes after orthopedic interventions. Syndrome dysmenorrheic. Threat of premature birth.

Adverse effects occur in 30-60% of patients treated with Indomethacin, and in the 10% of patients, these effects are as severe ones that require the discontinuity of treatment. The most important effects involve the central nervous system and tract gastrointestinal. • Neurological reactions are: headache, dizziness, depression, vertigo, and fatigue. El headache is the most common and severe effect in the mornings and may be accompanied by frontal palpitations. Less frequently: mental confusion, anxiety, drowsiness, seizures, coma, peripheral neuropathy, muscle weakness. Rarely: paresthesia and worsening of epilepsy and parkinsonism. • Gastrointestinal symptoms: Nausea, anorexia, vomiting, epigastric discomfort, apparent bloating, constipation and diarrhea. very stomatitis, flatulence or hemorrhages of sigmoid origin. • Hepatic: rarely do symptoms of hepatitis or jaundice with administration of Indomethacin. • Cardiovascular or renal: with little edema frequency, increased pressure arterial, tachycardia, chest pain, arrhythmia, hypotension, congestive heart failure. • Hypersensitivity reaction: with signs of skin rashes, exfoliative dermatitis, pruritus, hives, acute respiratory disorders, dyspnoea. • Hematic: there may be: leukopenia, petechiae, thrombocytopenic purpura. • Other reactions: hearing disorder, proteinuria, interstitial nephritis, hyperglycaemia, glucosuria, blurred vision and orbital pain or periorbital. Bronchoconstriction in asthmatics sensitivity to acetylsalicylic acid

It is contraindicated in patients with recognized hypersensitivity to the drug. In patients with nasal polyps associated with angioedema or reactions acid-precipitated bronchospastic acetylsalicylic or other anti-inflammatory drugs no steroidal. In active gastroduodenal ulcer, lesions recurrent gastric diseases, first trimesters of pregnancy, lactation, children under 14 years old.

Indomethacin inhibits aggregation platelet, so this effect should be taken into account in patients with disorders of coagulation or under therapy with blood thinners. Use with caution in patients with defects in coagulation, hypertension, heart failure congestive, moderate renal impairment or with history of psychiatric illnesses, epilepsy, Parkinson's, since the drug can aggravate these conditions. It should be used with caution in Elderly people because the incidence of reactions adverse events seem to increase with age. Indomethacin may cause dizziness and may Decrease the ability to carry out activities that require mental alertness or physical coordination (operating machinery, driving vehicles, etc.). Gastrointestinal disorders are Minimize when the medication is ingested after meals or associated with antacids. If intestinal bleeding occurs, will stop treatment. In prolonged treatments it should be monitored on a periodic basis the blood formula and liver function, since Indomethacin has hepatotoxic effects. Pregnancy: Indomethacin is contraindicated in pregnancy. Breastfeeding: Indomethacin is not recommended for nursing mothers. It should be used with caution in patients with renal failure or with sodium retention associated with liver disease or heart failure.